中译英

目前对镁合金表面改性的方法很多，包括化学转化法、离子注入法、气相沉积和阳极氧化法等，这些方法主要改善镁合金的耐蚀性能而非生物活性，因此通过这些方法制备的生物活性涂层始终没有达到理想的临床效果。
    弧氧化(micro-arcoxidation，MAO)又称微等离子体氧化，是一种直接在有色金属表面原位生长陶瓷涂层的新技术，所形成的生物活性涂层具有耐腐蚀性能高、耐磨损性能好等特点，与其它材料表面改性技术相比，微弧氧化具有工艺简单、不受工件表面形状限制的特点，更重要的是，微弧氧化涂层与基体结合强度高，植入体内不易脱落，而且通过微弧氧化能够将生物活性元素掺杂进入微弧氧化涂层，在改善镁合金耐腐蚀性能的同时，能够提高镁合金的生物相容性和生物活性，具有很好的临床应用前景.

锌（Zn）是人体必需的微量元素之一，广泛存在于骨组织中，能够有效促进成骨细胞的增殖和骨基质中胶原的合成,并对破骨细胞的形成有潜在的抑制作用。研究表明适量的锌既能促进成骨细胞的增殖与分化，同时又使成骨细胞的凋亡受到抑制，因此锌对骨骼的作用引起了研究人员的高度重视。基于以上原因，本研究拟通过微弧氧化技术在镁合金表面制备含锌的生物活性涂层，同时采用扫描电镜(SEM)、能谱仪(EDS) 和X射线衍射仪(XRD)分析膜层的形貌、生物活性锌元素含量及物相组成，通过溶血试验评价含锌微弧氧化涂层的生物相容性，期望为镁合金的临床应用提供一种新的思路和方法。

Currently, there are many methods for surface modification of magnesium alloys, such as chemical conversion, ion implantation, vapor deposition and anodic oxidation process. These methods mainly improve the corrosion resistance but not biocompatibility. Bioactive coatings on the surface of magnesium alloys prepared by these methods  usually fail to the meet the clinical standard.

Micro-arc oxidation (MAO), also known as micro-plasma oxidation, is a new technology that produces ceramic coating in-situ on the surface of nonferrous metals. Bioactive coatings formed this way have high corrosion and abrasion resistance. Compared with other technologies of surface modification, MAO has the advantages of simplicity and nolimitations from the shape of workpiece. MAO coating can bind strongly to the substrate and the implant with MAO coating is not easy to detach. While enhancing the corrosion resistance, MAO can be also used for the doping of bioactive elements into the coating to improve the biocompatibility and bioactivity of the magnesium alloys.

Zinc (Zn) is a necessary trace element for the human body and widely present in bone tissues. It can promote osteoblast proliferation and collagen synthesis in bone matrix, while potentially inhibiting osteoclast formation. It is revealed that an appropriate amount of Zn can promote osteoblast proliferation and differentiation and inhibit osteoblast apoptosis. The importance of Zn in bone is generally recognized. In this study, we prepared Zn-containing bioactive coating on magnesium alloys using MAO. Surface morphology, content of zinc content and phase composition of the bioactive coating were investigated by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and X-ray diffraction (XRD), respectively. Biocompatibility of the zinc-containing coating was analyzed by hemolysis test. The findings are expected to provide valuable clues for clinical use of magnesium alloys.